The effect of pantothenic acid dosage and environmental temperature and humidity upon the dermal and renal excretion of pantothenic acid.

نویسندگان

  • H SPECTOR
  • T S HAMILTON
  • H H MITCHELL
چکیده

The loss of considerable amounts of water-soluble nutrients in the sweat would have an important bearing on nutrition in the tropics and in hot humid seasons of the year in the temperate zone, provided these losses represented something more than a mere diversion of excretion from kidney to sweat glands. The possibility of such losses has stimulated considerable research in recent years, particularly studies of the vitamin content of sweat. The present paper, concerned with the manner of excretion of pantothenic acid by adult man on different levels of intake, is one of a series of papers on this general subject from this laboratory. Its significance in practical human nut,rition cannot be assessed until the essentiality of pantothenic acid in the human diet has been more firmly established. The evidence on this point recently reviewed by Gordon (1) leaves much to be desired. In this connection it may be pointed out that the demonstration of a therapeutic value of a substance does not necessarily imply that a dietary deficiency has been thus corrected by it.

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عنوان ژورنال:
  • The Journal of biological chemistry

دوره 161  شماره 

صفحات  -

تاریخ انتشار 1945